Irene Ruth Billo was born on 22 September 1916, the daughter of Otto Billo, an international businessman who was among the first Swiss to meet Meher Baba. In 1936 she came upon Baba's photograph in her father's secret cupboard and was struck as if Baba himself were present; from then on she attended the meetings of Baba's Swiss followers at the home of Hedi Mertens.
In August 1937, when Baba was staying at Cannes and help was needed in the household, Hedi sent the twenty-year-old Irene. At the Villa Caldana she cleaned Baba's room and did the grocery shopping, and she felt she had come home. She asked whether she too might go to India one day, and Baba said yes. On 28 June 1938 she arrived in Bombay with Nadine Tolstoy, Hedi Mertens and the painter Helen Dahm, the youngest of the Western women, and joined the women's ashram on Meherabad Hill. Soon after arriving she fell ill with jaundice and, by Baba's order, Rano Gayley nursed her back to health. Baba gave her the name Padmini, "lotus"; in India she was called Padma.
Irene had been raised to be practical. She sewed clothes for the patients of the hospital on the Hill, taught the Dastoor sisters to make their own clothes, and cared for the animals Baba gathered: horses, donkeys, dogs, geese and even pigs. Her love of animals and her sewing brought her close to Mehera. She travelled with the women on the Blue Bus tours, keeping a year of silence on Baba's order as Mansari did, and stayed with Baba and the women at Meherabad, Mahabaleshwar and elsewhere. When her father died at the end of October 1940, Baba told her he had been very lucky and was free.
Baba had told her, "You come for two years," but she remained eight. In March 1946 he sent her back to Switzerland. Her family's fortunes had declined, and she worked as a telephone exchange operator for Siemens, later training blind operators. When Baba came to Switzerland in 1952 after his car accident in America, Irene met him at the airport and helped Hedi Mertens host him and the women; in 1956 she arranged his stopover in Zurich, where about 35 Europeans met him, and accompanied him to London.
In 1983 Irene returned to India for the first time in 37 years, visited Mehera and the women mandali at Meherazad, and spent hours on Meherabad Hill with Mansari, saying it felt as if Baba had gone to Nasik and would be back next week. She died on 25 July 1986.